PGT-A, PGT-M, PGT-SR explained
PGT-A (aneuploidy) screens for whole-chromosome errors that cause failed implantation or miscarriage.
PGT-M (monogenic) tests for specific inherited single-gene disorders when a parent is a known carrier.
PGT-SR (structural rearrangement) detects unbalanced translocations in couples with known balanced rearrangements.
Patient selection
- Advanced maternal age (≥38) with elevated aneuploidy risk
- Recurrent pregnancy loss with documented aneuploid losses
- Recurrent IVF implantation failure
- Known parental balanced translocation
- Known inherited genetic condition with family history
What PGT cannot do
PGT-A reduces miscarriage rates and time to live birth in older women but does not increase cumulative live birth rates in all populations. Biopsy carries small risk of embryo damage. Mosaicism complicates results in 15-20 percent of biopsies.
PGT explained
| Type | Detects |
|---|---|
| PGT-A | Aneuploidy (chromosome number) |
| PGT-M | Single-gene conditions |
| PGT-SR | Structural rearrangements |
Our IVF practice follows international reproductive-medicine standards.
Frequently asked
Dr Patel leads fertility care at Balaji Horizon, integrating reproductive surgery and IVF into a single plan — ethical, evidence-based and individualised, with realistic expectations and no overpromising of success.
Individualised IVF and fertility planning with honest, evidence-based counselling — and realistic expectations from the very first consultation.
PGT — who genuinely benefits, and its limits
Pre-implantation genetic testing (PGT) examines embryos for chromosomal or specific genetic conditions before transfer. It is a powerful tool for the right indication, not a routine upgrade for every cycle.
When it is appropriate
PGT-A (for chromosome number) is most defensible with advanced maternal age, recurrent miscarriage or repeated implantation failure; PGT-M tests for a known inherited single-gene condition in the family; PGT-SR is for a known chromosomal rearrangement. Each answers a different, specific question.
Honest limits
PGT requires an embryo biopsy and good blastocyst numbers, can occasionally give uncertain (mosaic) results, and does not guarantee a baby — it reduces the chance of transferring an affected embryo but cannot create chromosomally normal embryos that were never there. For younger women with good-quality embryos, routine PGT-A does not reliably increase live-birth rates.
Our approach
We recommend PGT where the indication is clear and counsel you fully on what a result will and will not tell you, including how mosaic or no-result embryos are handled, before you commit.
Dr. Priyadatt Patel
Senior Gynecologist · Advanced Laparoscopic Surgeon · IVF and Endometriosis Programme Lead
MS OBGyn · Pregnancy Care · Advanced Gynaecological Ultrasound · Fertility Preservation
ESHRE / ESGE / AAGL / ASRM guideline-aligned practice. 3D Karl Storz precision technique. Fertility-preservation-first philosophy. Evidence-based decisions, honest counselling, long-term outcomes orientation.
Science City Road, Ahmedabad 380060
Mon–Sat 11:00–20:00 · +91 97234 31544
Naranpura, Ahmedabad
Mon–Sat 08:30–10:30 · +91 70460 02566
