Part of Advanced ART & Reproductive Technologies
PGT — Preimplantation Genetic Testing
Embryos can be screened for chromosomal abnormalities (PGT-A), specific gene disorders (PGT-M), or structural rearrangements (PGT-SR) before transfer. Powerful when indicated. Wasteful when not.
Three Types of PGT
PGT-A screens for aneuploidy (extra/missing chromosomes) — useful for advanced maternal age and recurrent miscarriage. PGT-M tests for a specific known genetic disorder in the family (e.g. beta-thalassemia, cystic fibrosis). PGT-SR is for parents who carry a known chromosomal rearrangement (translocation, inversion).
When We Use It
- Advanced maternal age (≥38)
- Recurrent pregnancy loss
- Repeated implantation failure
- Known genetic disease in family (PGT-M)
- Known parental chromosomal rearrangement (PGT-SR)
- Sex selection ONLY for sex-linked disorder transmission (medical only)
PGT-A for routine IVF in younger women does NOT consistently improve outcomes. We discuss expected benefit honestly before recommending PGT.